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Guidetti, Martina; Zampini, Marco Andrea; Jiang, Yizhou; Gambacorta, Chiara; Smejkal, Joshua P.; Crutison, Joseph; Pan, Yayue; Klatt, Dieter; Royston, Thomas J. (, Journal of the Mechanical Behavior of Biomedical Materials)null (Ed.)
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Guidetti, Martina; Klatt, Dieter; Royston, Thomas J. (, IEEE International Symposium on Biomedical Imaging (ISBI) 2020)Elastography refers to mapping mechanical properties in a material based on measuring wave motion in it using noninvasive optical, acoustic or magnetic resonance imaging methods. For example, increased stiffness will increase wavelength. Stiffness and viscosity can depend on both location and direction. A material with aligned fibers or layers may have different stiffness and viscosity values along the fibers or layers versus across them. Converting wave measurements into a mechanical property map or image is known as reconstruction. To make the reconstruction problem analytically tractable, isotropy and homogeneity are often assumed, and the effects of finite boundaries are ignored. But, infinite isotropic homogeneity is not the situation in most cases of interest, when there are pathological conditions, material faults or hidden anomalies that are not uniformly distributed in fibrous or layered structures of finite dimension. Introduction of anisotropy, inhomogeneity and finite boundaries complicates the analysis forcing the abandonment of analytically-driven strategies, in favor of numerical approximations that may be computationally expensive and yield less physical insight. A new strategy, Transformation Elastography (TE), is proposed that involves spatial distortion in order to make an anisotropic problem become isotropic. The fundamental underpinnings of TE have been proven in forward simulation problems. In the present paper a TE approach to inversion and reconstruction is introduced and validated based on numerical finite element simulations.more » « less
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Guidetti, Martina; Caratelli, Diego; Royston, Thomas_J (, The Journal of the Acoustical Society of America)A theoretical approach was recently introduced [Guidetti and Royston, J. Acoust. Soc. Am. 144, 2312–2323 (2018)] for the radially converging slow shear wave pattern in transverse isotropic materials subjected to axisymmetric excitation normal to the axis of isotropy at the outer boundary of the material. This approach is enabled via transformation to an elliptic coordinate system with isotropic properties. The approach is extended to converging fast shear waves driven by axisymmetric torsional motion polarized in a plane containing the axis of isotropy. The approach involves transformation to a super-elliptic shape with isotropic properties and use of a numerically efficient boundary value approximation.more » « less
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